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Many patients managing osteoporosis are looking for treatments that offer both effectiveness and convenience. Reclast is a trusted option that helps strengthen bones, reduce fracture risk, and improve overall bone health—delivered just once a year through IV infusion.

At Denver Arthritis Clinic’s Infusion Center, we specialise in infusion therapy for osteoporosis, including Reclast IV infusions, right here in Denver. Our experienced team provides evidence-based care in a setting built for comfort and peace of mind. To learn if Reclast is the right fit for you, call us today or schedule an appointment online.

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Here’s what you need to know about how Reclast works, what to expect during treatment, and important safety considerations.

How Reclast Works to Treat Osteoporosis

Reclast (zoledronic acid) is designed to treat osteoporosis by targeting the cells responsible for breaking down bone. In healthy bone, there’s a balance between bone breakdown and formation. In osteoporosis, breakdown outpaces formation, leading to decreased bone mass and increased fracture risk.

Reclast slows this process by:

  • Binding to bone and inhibiting the activity of osteoclasts, the cells that break down bone
  • Reducing bone resorption, allowing bone-building cells to restore strength
  • Increasing bone mineral density, particularly in the spine and hips

As a result, Reclast IV infusion helps strengthen bones and lowers the likelihood of serious fractures over time.

The Reclast Infusion Process: What to Expect

Reclast infusions are given once a year as a 15-minute intravenous (IV) treatment. This low-frequency dosing schedule is convenient for patients seeking a long-term solution without daily or weekly medications.

Here’s what to expect during a typical appointment at our Denver Infusion Center:

  1. Pre-Infusion Screening
    • Your provider will review your medical history, lab results (including kidney function), and vitamin D levels.
    • Reclast is not recommended for patients with severe kidney problems or low calcium.
  2. During the Infusion
    • The IV infusion for osteoporosis is delivered over approximately 15 minutes.
    • You’ll be comfortably seated under the care of our infusion team.
  3. Aftercare
    • Most patients can resume normal activity immediately.
    • Drinking plenty of fluids before and after the infusion is encouraged to support kidney function.

We work closely with referring providers to ensure each patient’s treatment is appropriately timed and monitored for safety.

Benefits and Timeline for Bone Health Improvement

The benefits of Reclast infusions are backed by clinical research and patient experience. These include:

  • Increased bone density in the spine and hip
  • Reduced risk of fractures, particularly in postmenopausal women
  • Convenient once-yearly dosing
  • Fewer gastrointestinal side effects compared to oral bisphosphonates

Most patients begin to see improvements in bone mass and strength within 6 to 12 months. Long-term use has shown continued protection against bone fractures with annual treatment.

Potential Side Effects and Precautions of Reclast IV Infusion

Reclast IV infusion therapy can help improve and protect bone health, but like any medical treatment, there are potential side effects to consider. Most side effects are mild and go away within a few days, while rare complications may require medical attention. Here's what you should know:

Common Side Effects

These side effects are typically mild and temporary, resolving within a few days after the infusion:

  • Flu-like symptoms: Fever, chills, muscle aches, and fatigue, especially after the first dose.
  • Bone, joint, or muscle pain: Often mild to moderate, with some patients experiencing a dull, aching discomfort.
  • Mild muscle spasms or bone pain.
  • Injection site reactions: Redness, swelling, or tenderness where the IV was administered.
  • Headache and nausea.

Less Common but Serious Risks

While rare, the following side effects may occur:

  • Kidney problems: Severe kidney complications, including acute kidney injury, may develop, especially in patients with existing kidney issues or dehydration.
  • Low calcium levels (hypocalcemia): Can cause muscle spasms, numbness, or tingling, particularly if calcium or vitamin D levels are low.
  • Severe bone, joint, or muscle pain: This can occur days to weeks after infusion and may be intense in rare cases.
  • Jawbone damage (osteonecrosis): This is rare and often linked to patients undergoing dental surgery or with poor oral health.
  • Atypical thigh bone fractures: Very rare, but potential fractures can occur without significant trauma.

Precautions to Keep in Mind

Reclast is a safe and effective treatment for many patients, but certain precautions should be taken to reduce risks:

  • Hydration is key. Drinking at least two glasses of water before the infusion and staying hydrated afterward supports kidney function and reduces the likelihood of dehydration-related complications.
  • Calcium and Vitamin D are vital. Adequate intake helps maintain healthy calcium levels and reduces the risk of hypocalcemia. Your healthcare provider may recommend supplements two weeks before and after treatment.
  • Kidney health monitoring is essential. Patients with existing kidney impairment or those taking medications that affect the kidneys should discuss this with their provider. A blood test may be performed to assess kidney function before the infusion.
  • Dental health matters. Maintain good oral hygiene and complete any major dental work before starting Reclast. Notify your dentist about your treatment to minimize the risks of jawbone complications.
  • Pregnancy and breastfeeding are contraindications. Reclast should not be used during pregnancy or breastfeeding, as it may pose risks to the baby.

When to Contact Your Provider

If you experience severe symptoms like unusual pain in the thighs or hips, persistent flu-like symptoms, reduced urination, or symptoms of low calcium (such as muscle cramps or tingling), notify your healthcare provider immediately. These may indicate complications that require further evaluation.

The skilled team at the Denver Arthritis Clinic is here to guide you through every aspect of your treatment, answering your questions and addressing any concerns. Together, we’ll ensure that your course of treatment fits your health needs while supporting your long-term bone health.

Why Choose the Infusion Center at Denver Arthritis Clinic

At the Denver Arthritis Clinic Infusion Center, we provide safe, evidence-based osteoporosis treatments in a setting designed for comfort and peace of mind. Our team includes board-certified rheumatologists and experienced infusion nurses who monitor every step of your treatment.

We offer:

  • Expert administration of zoledronic acid (Reclast)
  • Collaboration with your primary provider or specialist
  • Flexible scheduling options
  • A patient-first approach that prioritizes your comfort and outcomes

Whether you’re newly diagnosed or switching from oral medication, our infusion team is here to support you on your path to stronger, healthier bones.

Strengthen Your Bones with Reclast at Denver Arthritis Clinic

Reclast IV infusion is a proven treatment that helps protect bone health and prevent fractures over time. Our team at Denver Arthritis Clinic is here to guide you through every step of your osteoporosis care with expertise and support.

Call our Infusion Center at 303.394.2828 or schedule your appointment online to learn more about how Reclast infusion therapy can support your long-term bone strength.

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